In the initial stage of process development, pharmaceutical companies often have the following pain points, considering factors such as R&D costs, laboratory conditions, process uncertainty, and future process transfer:
· High experimental operation requirements and low error tolerance rate;
· System automation is low;
· Data collection is difficult and the amount of data is small;
· Process testing costs are high;
· Yield is difficult to control and reproducibility is poor;
Cobetter took this as its original design intention and focused on solving many problems encountered in R&D testing. It developed and designed the Minilab small TFF ultrafiltration system to better support the R&D process of pharmaceutical companies.
Features
· Small running volume and low testing cost; can be freely and flexibly matched;
· Can be adapted to two types of consumables: hollow fiber membrane or membrane cassette;
· Can match a variety of different brand products;
· Powerful function, can realize a variety of process operations;
· A variety of data can be collected and recorded;
· Suitable for basic process development at the R&D end;
Components
Minilab TFF system has the characteristics of free combination and flexible matching, and can adapt to various complex usage environments of clients. Its system components include the following parts.
![Figure: Cobetter Minilab TFF Tangential Flow Filtration System](https://cdn.shopify.com/s/files/1/0666/9939/5371/files/Cobetter-MiniLab-Ultrafiltration-System_600x600.jpg?v=1704449267)
Figure: Cobetter Minilab TFF Tangential Flow Filtration System
System Functions
Constant TMP control;
Constant ∆P control;
NWP calculation;
Continuous/discontinuous concentration;
Shear rate calculation;
Recipe management;
Batch management/report management;
Data processing/data export/trend analysis;
Equal volume filtration;
System Parameters
Compatible Consumables | Minilab |
Hollow fiber |
Mini 30cm / Mini 60cm Minilab 30cm / Minilab 60cm |
Consieve UET |
Consieve UET 0.01m² Consieve UET 0.1m² |
Maximum Flow Rate | |
Main pump | 3400 ml/min |
Auxiliary pump | 480 ml/min |
Other | |
Connection material | 13# 14# 16# |
Compatible holders | 0.01m² |
Space required | Desktop |
Minimum operating volume | 20ml |
Standard instruments |
Pressure transmitter Balance |
Tank volume | 500ml |
Self-control mode |
Constant TMP control Constant ∆P control Equal volume washing rule Continuous concentration Inline NWP |
Power supply | 220V |
Applicable scene |
Lab R&D Process development |