Vaccines

There is a wide variety of vaccines depending on the type of antigen. But the vaccine manufacturing process is similar for all types. Production of vaccines is a complex process involving many different steps and processes. The most common method of vaccine production is based on an initial fermentation process followed by purification.
Cobetter's products support the production of traditional vaccines and emerging technologies such as recombinant vaccines.

Vaccine Types

Virus based vaccines

Viral vector vaccines

Nucleic Acid Vaccines

Recombinant protein vaccines

Virus based vaccines

Viral vector vaccines

Nucleic Acid Vaccines

Recombinant protein vaccines

Cell Culture Media Filtration

Filtration of cell culture media is very important as it can mitigate contamination risks and increasing product yield. Cobetter provides a wide range of filters of cell culture media filtration in biopharmaceutical manufacturing.

Clarification

Clarification of vaccines is a critical step that strongly impacts product recovery and subsequent downstream purification. Cobetter Roheap depth filters provides economic and efficient removal of cell debris and negatively charged molecules.

Roheap® CSD

Excesal® CHE -PP

Excesal® CHT -PP

Greclary® CHV -Glass Fiber

Excesal® CHC -PP

Buffer Filtration

Biopharmaceutical manufacturing requires large volumes of buffers for different steps in downstream processing. Cobetter offer different filters dependent on the needs of the specific process step.

Purcise® PLE -Double Layer PES

Safetect® PME -PES

Purcise® SLE -Double Layer PES

Corevital® PMD -PVDF

Purcise® PAF -PES

Purcise® SAF -Double Layer PES

Purcise® SPS -PES

Tangential-Flow filtration

Ultrafiltration is important steps throughout bioprocessing to increase concentration and recovery. Cobetter Tangential-Flow Filtration portfolio includes filters, holders, and systems. More important, single-pass TFF is being implemented in continuous or intensified processes to reduce in-line volumes.

Consieve®UET TFF -PES&RC

TFF Holders

Single-pass TFF

Hollow Fiber TFF

Final Sterile Filtration

Cobetter provide advanced sterile filters to speed up your process development and complete your process validation. Our 0.2 µm sterilizing-grade PES filters offer high flux, and 0.22 µm sterilizing-grade PVDF filters and are robust and low protein binding.

Purcise® SLE -Double Layer PES

Corevital® SMD -PVDF

Purcise® SPS -PES