Syringe Filters

Syringe Filters


Color-coded Syringe Filters

Cobetter color-coded syringe filters are ideal for particle removal with a sample volume of 1-200mL.


  • Nylon Syringe Filter---Low extractable. Filtration of mixed solvents and solvents.
  • PES Syringe Filter---High flow rate. Filtration of tissue culture media.
  • PVDF Syringe Filter---Low protein binding. Compatible with protein solutions and mild organic solutions.
  • PTFE Syringe Filter---Maximum chemical resistance. Filtration of mixed solvents and solvents.
  • PP Syringe Filter---Broad range of pore sizes. Prefiltration and solvent filtration.

Select by Volume

Sample Volume
Filter Diameter Filtration Area Hold-up Volume Retention Volume
< 10mL 13mm 0.72 cm² < 25μL < 25mL
10mL to 100mL 25mm 4.5 cm² < 100μL < 100mL
100mL to 200mL 33mm 4.5 cm² < 125μL < 125mL

HPLC-certified Syringe Filters

Cobetter white Hydrophilic PTFE syringe filters are HPLC-certified for low levels of UV-absorbing extractable.  

         Cobetter Hydrophilic PTFE Syringe Filters with Low Extractables

Sterile Syringe Filters

Cobetter sterile syringe filters are ideal for sterile filtration of cell culture media with a high flow rate and low protein adsorption.


  • 0.1 µm for mycoplasma filtration
  • 0.22 µm for sterile filtration
  • 0.45 µm for clarification
  • 0.8 µm for particle and yeast cell removal 

                 Cobetter Sterile PES Syringe Filters with High Flow Rate

How to use a syringe filter?

Choose the right type of membrane material based on the properties of your sample. Be careful of the chemical compatible to avoid extractables and leachables. Read this article about: How to choose a syringe filter?

1. Load the sample into the syringe.

2. Attach the filter to the luer-lock of the syringe with a twisting motion. Make sure it is securely attached.

3. Filter the sample. Hold the syringe and filter vertically, and gently press the plunger to push the sample through the filter. Take care not to apply too much force or you may damage the filter.

4. Discard the used filter and repeat for next sample.

how to use a syringe filter?

How to sterilize syringe filters?


Only autoclavable syringe filters can be autoclaved. They can withstand autoclaving at 121°C (up to a maximum of 130°C) for 30 minutes, and this process can be repeated up to 20 times. However, we recommend using it only once for optimal performance after autoclaving. 

Gamma Irradiation

Gamma irradiation involves exposing the filters to high-energy gamma rays, which can kill microorganisms such as bacteria, viruses and fungi. This method is typically used for large-scale sterilization in a relatively short time. Cobetter sterile syringe filters are gamma irradiated and individually packed.

Additionally, be sure to handle the filters with clean gloves or use it in the clean bench to avoid introducing contaminants while using.

Related Articles

How to Choose a Syringe Filter?

Are Syringe Filters Single-use?

  • Chemical_Compatibility_Chart_for_Syringe_Filters Download
  • Cobetter_Laboratory_Filtration_Products_2024 Download

Q1: Can syringe filters be reused?

No, it is disposable. Once a syringe filter was reused, it would cause contamination risk of the sample.

Q2: What’s the shelf life of syringe filters?

Cobetter syringe filter’s shelf life is 3 years.

Q3: Can you autoclave syringe filters?

No, it is not recommended.

Q4: What is the maximum operating temperature of syringe filters?

The maximum recommended operating temperature is 60°C.

Q5: Why should I use a syringe filter that has a prefilter layer?

The prefilter layer can reduce particle loading. Applications containing high levels of particulates need syringe filters with multiple layers of membrane, which usually have greater total throughput when compared with single-layer ones.