DN66TC /NY6TC Sterilizing-Grade Liquid Filter
The membrane of the DN66TC / NY6TC cartridge is made of hydrophilic nylon 66, which is mainly used for bio-burden reduction and sterile filtration of the final material. The nylon cartridge can filter ammonia, methyl ethyl ketone, cyclohexanone and other solvents with good chemical stability.
Recommended Applications:
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Description
Features
- Not charged
- Naturally hydrophilic
- Low adsorption
Applications
- Pharmaceutical sterile filtration
- Solvent filtration
- Alkaline filtration
Quality
- 100% Integrity testing in manufacturing
- Each filter is fully traceable with unique serial number
- Manufactured in a facility which adheres to ISO 9001:2015 Practices
Flow Rate Characteristics

Specifications
Materials of Construction
Membrane | Nylon 66 |
Support | Polypropylene (PP), polyester (PET) |
Core/Cage/End Caps | Polypropylene (PP) |
End Cap Inserts | Polybutylene terephthalate (PBT) |
Seal Material | Silicone / EPDM / Viton FEP/ PFA encapsulated O-rings |
Operating Conditions
Max. Operating Temperature |
80°C |
Max.Operating Pressure |
0.69 MPa@25°C 0.40 MPa@60°C 0.24 MPa@80°C |
Max. Differential Pressure (Forward) |
0.69 MPa@25°C 0.40 MPa@60°C 0.24 MPa@80°C |
Max. Differential Pressure (Reverse) |
0.30 MPa@25°C 0.10 MPa@80°C |
Filtration Area
Outer Diameter | Membrane Pore Size | Area/10" | |
DN66TC | 71 mm | 0.22+0.22 μm | 0.62 m² |
71 mm | 0.45+0.22 μm | 0.62 m² | |
71 mm | 1.0+0.45 μm | 0.62 m² | |
NY6TC | 71 mm | 0.22 μm | 0.84 m² |
69 mm | 0.45 μm | 0.68 m² |
Integrity Test Standards @10inch,20°C (DN66TC)
Mmembrane Pore Size | Bubble Point | Diffusion Flow (Air) |
0.22+0.22 μm | ≥ 0.30 MPa (water), Air test | / |
0.45+0.22 μm | ≥ 0.30 MPa (water), Air test | / |
1.0+0.45 μm | ≥ 0.14 MPa (water), Air test | / |
Integrity Test Standards @10inch,20°C (NY6TC)
Membrane Pore Size | Bubble Point | Diffusion Flow (Air) |
outer diameter 71 mm-0.22 μm | ≥ 0.32 MPa, Wetted with water, Air test | / |
0.45 μm | ≥ 0.14 MPa, Wetted with water, Air test | / |
Bacterial Retention
Model | Content |
DN66TC 0.22+0.22 μm | Bacterial quantitative retention of 10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) accordingto ASTM F838 methodology. |
DN66TC 0.45+0.22 μm | |
71NY6TC 0.22 μm | Bacterial quantitative retention of 10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) accordingto ASTM F838 methodology. |
71NY6TC 0.45 μm | Bacterial quantitative retention of 10⁷ cfu/cm² Serratia marcescens (ATCC14756) according to ASTM F838 methodology. |
Sterilization
In-line steam sterilization | Up to 50 cycles (121 °C for 30 minutes and differential pressure <30KPa per cycle ) |
Regulatory Compliance
- Autoclaved filter effluent meets the USP<788> requirement of particulate matter in large volume injection.
- Component materials meet the criteria for a "Non-fiber-releasing filter" as defined in 21 CFR 210.3(b)(6).
- Aqueous extraction from a cartridge contains less than 0.25EU/ml as determined by Limulus Amebocyte Lysate (LAL), meeting requirements of USP<85>.
- Meet the requirement of USP <87> In Vitro Cytotoxicity Test.
- Component materials meet the requirements of the current USP<88> for plastic class VI-121°C.
- All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182.
- Based on the current information from our suppliers, all component materials used in the manufacture of this product are animal-free.
End Cap

Ordering Information
DN66TC (Double -layer)
Outer Diameter | Type | Membrane Pore Size | End Cap | Nominal Length | Seal Material | Industry |
69mm | DN66TC | 2222 0.22+0.22 µm | DOE Double Open End | 05 5 inch | S Silicone | P |
71 71mm | 4522 0.45+0.22 µm | HTF 222/Fin (PBT insert) | 10 10 inch | E EPDM | ||
1045 1.0+0.45 µm | HSF 226/Fin (PBT insert) | 20 20 inch | V Viton | |||
HTCG 222/Flat (PBT insert) | 30 30 inch | P FEP/PFA encapsulated O-rings | ||||
HSCG 226/Flat (PBT insert) | 40 40 inch |
NY6TC (Single-layer)
Outer Diameter | Type | Membrane Pore Size | End Cap | Nominal Length | Seal Material | Industry |
69mm | NY6TC | 0010 0.1 µm | DOE Double Open End | 05 5 inch | S Silicone | P |
71 71mm | 0022 0.22 μm | HTF 222/Fin (PBT insert) | 10 10 inch | E EPDM | ||
0045 0.45 μm | HSF 226/Fin (PBT insert) | 20 20 inch | V Viton | |||
0065 0.65 μm | HTCG 222/Flat (PBT insert) | 30 30 inch | P FEP/PFA encapsulated O-rings | |||
0080 0.8 μm | HSCG 226/Flat (PBT insert) | 40 40 inch | ||||
0100 1.0 μm | ||||||
0300 3.0 μm | ||||||
0500 5.0 μm |
* Example:DN66TC2222DOE05SP (DN66TC,0.22+0.22µm,Double open end,5 inch,Silicone,Pharmaceutical)