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COBETTER Lifecube® Single-Use Filter Sets with Tubing Plugs

In stock
Part No. SAF01009
$70.40 USD
$88.00 USD $70.40 USD
Port1+Port2
Tubing
Capsule Filter
*Ships within 3 Weeks
*Read our Shipping Policy and Refund Policy
Connections Port 1 Tubing Plug
Port 2 Tubing Plug
Dimensions Tube Length 50/100/250 cm
Tube Size 1/8'' ID - 1/4'' OD, 1/4'' ID - 7/16'' OD, 3/8'' ID - 5/8'' OD
Physical Properties Tubing Material C-Flex® 374 TPE
Filter Material Purcise® SLE polyethersulfone (PES) membrane
Pore size 0.2μm (with 0.45μm prefilter)
Filter Type
Bricap® C01 Bricap® C03 Bricap® L05 Bricap® L10
EFA
180cm² 660cm² 0.28m² 0.55m²
Sterility Delivery Condition Sterile
Sterilization Method Gamma Irradiation
Package Pack Size 1 set


Cobetter Lifecube® single-use tubing assemblies are used for interconnection of different unit operations in a wide range of applications. With our tubing assemblies, you can easily connect multiple containers, vessels and process lines in one system, minimizing the risk of cross-contamination, saving time and reducing costs.

C-Flex® is the original patented thermoplastic elastomer tubing specifically designed to meet the critical demands of pharmaceutical and biopharmaceutical applications for fluid processing with excellent heat seal and sterile weld capabilities.

The Lifecube® single-use filter sets consist of a 0.2 micron validated sterilizing-grade Bricap® C/L capsule filter. The incorporated Purcise® SLE polyethersulfone (PES) membrane demonstrates very low protein
binding and 1-14 pH range.

Applications

Monoclonal antibodies (mAbs), vaccines, plasma, cell, and gene therapies, etc. At any process step for liquid buffer/media, or final product filtration.

Q: What's the application of STS platinum-cured silicone tubing?

Cobetter STS platinum-cured silicone tubing is designed to facilitate fluid transfer in many pharmaceutical and biopharmaceutical applications.

Q: How many internal diameters are available for platinum-cured tubings?

Cobetter STS platinum-cured silicone tubing is available in 7 different internal diameters ranging from 1/8" (3mm) to 3/4" (19mm).

Q: What's the sterility method?

Gamma irradiation and autoclave.

Q: Cobetter’s custom tubing assemblies are non-sterile, can customers sterilize it by themselves?

1. Yes, customers can sterilize only the tubing assemblies and the connectors, excluding any bags.

2. When customers sterilize the connectors and tubing, all ports should be opened, such as connector plugs and blind caps on clamps. After sterilization is completed, they can be connected and used.

3. Especially attention shall be taken that you will need to add an additional cable tie to offset the leakage risk caused by the high-temperature deformation of the original cable tie after off-line sterilization.

Q: What is the recommended length to be reserved for thermoplastic tubing for aseptic connection and aseptic sealing?

Cobetter's aseptic connection machine and aseptic sealing machine can achieve aseptic connection and disconnection in general environments. It is recommended to reserve a length of 15cm for each connection and disconnection.

Q: Can silicone tubing and pump tubing be used for organic solvent solutions?

Silicone tubing is not resistant to organic solvents.

For pump tubing, we need to confirm specific details of the process, such as pipe diameter, operating pressure, duration of use, and the acidity/alkalinity of the fluid being pumped. If organic solvents are involved, it is recommended not to choose silicone tubing and instead opt for pump tubing that is resistant to organic solvents.

Q: Will a single-use system that has been irradiated have any impact on the product? Can irradiation residues be detected in the irradiated items?

No. The irradiation dose is validated to ensure sterilization effectiveness. Moreover, the irradiation process only involves energy absorption and does not involve direct contact with the radiation source. Therefore, there are no issues of irradiation residues in the disposable system.

Q: Are the integrity testing of bags and tubings conducted together?

The pressure resistance of the bags and tubings is different. The bag can withstand a pressure of 0.02 kg. For the bag, we apply a gas pressure of around 0.015 bar or 0.02 bar after clamping with bag clamps. After a certain period, we measure the pressure decay. The tubing and fittings can withstand pressure of up to approximately 2 bar, and we apply a pressure of 1.6 or 1.7 bar to measure the pressure decay.

Q: How do the drawings correspond to the product packaging?

Each product shown on a drawing represents the product within one package. If separate packaging or simultaneous use of multiple products is required, they can be split/integrated into a single drawing.
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